You should use the MagickImageCollection class. Here is an example:
using (MagickImageCollection images = new MagickImageCollection())
{
MagickImage first = new MagickImage("first.png");
images.Add(first);
MagickImage second = new MagickImage("second.png");
second.Page = new MagickGeometry(50, 50, 0, 0);
images.Add(second);
MagickImage result = images.Merge(LayerMethod.Mosaic);
result.Write("output.png");
}